Ongoing research aims to confirm the mechanism by which ICP4 fluidizes the nucleus, which could indicate specific targets to counter viral replication.

To better understand BKPyV replication and ways to prevent it, researchers in the UAB Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney cells. Their ...

A research team at Ruhr University Bochum, Germany, has identified a previously unknown cellular mechanism crucial to the replication of coronaviruses: c-Jun N-terminal kinase (JNK) is activated ...

Zika virus (ZIKV) is a mosquito-borne orthoflavivirus that can cause birth defects, including microcephaly, a condition in which head and brain size are significantly reduced at birth. The collective ...

The cold season is in full swing, throats are scratchy and noses are running. We feel ill and hope it is not the flu. The ...

Herpes simplex virus partially liquifies the tightly packed, gel-like interior of human cell nuclei to copy itself faster, a ...

Viruses are entirely dependent on their hosts to reproduce. They ransack living cells for parts and energy and hijack the host's cellular machinery to make new copies of themselves. Herpes simplex ...

Human norovirus, a positive-strand RNA virus that is the leading cause of viral gastroenteritis accounting for an estimated 685 million cases and approximately 212,000 deaths globally per year, has no ...

Though Gilead Sciences made waves last June with a landmark FDA approval for its twice-yearly HIV preventive Yeztugo (lenacapavir), the first-in-class drug had previously been used as a long-acting ...

Zika virus hijacks a key protein implicated in brain development for its own replication. Researchers led by Associate Professor Priya Shah at the University of California, Davis (CA, USA), have ...

BK polyomavirus, or BKPyV, is a major cause of kidney transplant failure. There are no effective drugs to treat BKPyV. Research reveals new aspects of BKPyV replication, offering possible drug targets ...