A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...

Cryo-EM structure of the Giardia ribosome reveals a highly compact, GC-rich rRNA with eukaryotic r-proteins. (A) Structure of the Giardia ribosome with all the r-proteins colored (SSU, shades of blue ...

The protein factories in our cells – so-called ribosomes – have a central task: during a process known as translation, amino acids are linked together according to messenger RNA, forming a growing ...

Research by UC Santa Cruz molecular biologist Harry Noller and his collaborators has led to the first direct observations of the mechanism for protein synthesis in living cells. Their new findings on ...

A team at ETH Zurich developed a new peptide-based organocatalyst that handles macrocycle formation from start to finish.