Researchers developed DoriVac, a DNA origami-based vaccine platform that precisely arranges antigens and adjuvants to enhance ...

RNA vaccines saved millions of lives during COVID-19 but have limitations like waning immunity and complex production. Scientists are now testing a new platform called DoriVac, which uses folded DNA ...

One of the challenges of fighting pancreatic cancer is finding ways to penetrate the organ's dense tissue to define the margins between malignant and normal tissue. A new study uses DNA origami ...

Essentially DNA origami enables long strands of DNA to fold, through self-assembly, into any desired shape. (In the 2006 paper, Rothemund famously used the technique to create miniature DNA smiley ...

The central ingredient of therapeutic cancer vaccines is antigens, which are preferentially produced or newly produced (neoantigens) by tumor cells and enable a patient’s immune system to search and ...

Chemotherapy is the primary cancer treatment used today. It involves using cytotoxic agents which attack and kill cells that are rapidly dividing, like cancer cells. However, delivering these drugs ...

One of the challenges of fighting pancreatic cancer is finding ways to penetrate the organ's dense tissue to define the margins between malignant and normal tissue. A new study uses DNA origami ...

A coarse-grained model of the DNA origami lilypad used in the study. The tails hanging down indicate where redox reporters are located. For scale, the diameter of the disk is approximately 80 nm.

Illinois professor Bumsoo Han, left, and postdoctoral researcher Sae Rome Choi are authors of a new study exploring the use of DNA origami for better imaging of dense pancreatic tissue for cancer ...