Scientists at the National Institutes of Health have found a mechanism in the immune systems of mice that can lead to the development of autoimmune disease when turned off. The findings shed light on ...

Scientists have found a new piece in the puzzle that explains why B cells self-react in autoimmune disease—and, with it, a potential new treatment strategy. In an article published Sept. 29 in the ...

Autoimmune disease occurs from the body’s immune system attacking its healthy cells. Unfortunately, the mechanism that would normally prevent autoimmunity is not present in some individuals. T cells ...

Scientists have found a mechanism in the immune systems of mice that can lead to the development of autoimmune disease when turned off. The findings shed light on the processes that lead to the ...

A study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical molecular mechanism behind autoimmune and inflammatory diseases such as ...

Researchers have discovered that human proteins with an affinity for dermatan sulfate (DS) have the propensity to become autoantigens. In a companion article, the researchers also found that DS ...

Scientists at the Department of Infection and Immunity of the Luxembourg Institute of Health (LIH) revealed a novel mechanism through which the immune system can control autoimmunity and cancer. In ...

The ability of a human body to resist pathogenic factors is under control of immune cells, the most important of which are lymphocytes. The first subtype called effector lymphocytes, contacts with ...

The mammalian immune system has an extraordinary potential for making receptors that sense and neutralize any chemical entity entering the body. Inevitably, some of these receptors recognize ...

The unique role of citrullination in osteoclast differentiation and ACPA-induced osteoclast activation might explain important features of the gradual development of rheumatoid arthritis, including ...