Gene therapy that can cross the blood–brain barrier represents a non-invasive way to map gene expression in the brains of ...

To further the quantitative understanding of cellular decision making, Dr. Gregory Reeves and his team in the chemical engineering department have worked to interpret how a transcription factor ...

Sometimes, a small error in the sequence of DNA can lead to a very serious disease. Scientists have identified many mutations that arise in a single gene to cause an ...

In 2021, a technology developed at University of Michigan, called Seq-Scope, revolutionized the ability to map gene activity ...

Bionano Genomics and Greenwood Genetic Center have announced a study published in Genome Research, marking the first use of optical genome mapping (OGM) to explore the genetic factors behind neural ...

Some CREs are shared between genes but affect each gene differently, and a CRE that affects a gene's expression might be located far from the gene itself. "During this process, we were able to ...

Researchers identified three chromosome 21 genes that are overactive in brain cells of individuals with Down syndrome, and demonstrated partial molecular correction using antisense oligonucleotides.

The pathology of mental disorders is complex. Researchers can’t just attribute mental disorders to one or a few single mutations in a gene or protein — there are too many factors at play. After all, ...

Genetic data show that 14 psychiatric diagnoses cluster into five families of shared risk, explaining why conditions like depression and anxiety often occur together.

The genetics of autism has long been one of the most intricate puzzles in neurodevelopmental science. Today, the pieces are coming together more rapidly than ever before. Landmark projects such as the ...