Using human liver samples and a mouse model of cirrhosis, researchers identified epigenetic overactivation of the inflammatory PAF–PAF-R pathway in hepatic macrophages as a key driver of liver damage.

Never-before-seen 3D reconstructions of human liver tissue have been created at a cellular level. The details obtained by a team of UW Medicine and University of Washington engineers and physicians ...

Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...

The liver stands as a powerhouse organ, orchestrating a symphony of crucial functions essential for our overall health. It serves as the body’s primary detoxifier, meticulously removing harmful ...

More than 10,000 Americans who suffer from chronic liver disease are on a waitlist for a liver transplant, but there are not ...

Hepatitis B is one of the most widespread viral infections in the world, with hundreds of millions of people living with it today. Caused by the hepatitis B virus (HBV), this condition primarily ...

Injected liver cells stayed viable and functional for eight weeks in mice Can’t keep waiting on the transplant list? How ...

Scientists have developed injectable "mini livers" that can replicate liver function, potentially buying time for those with liver disease.

More than 10,000 Americans are waiting for a liver transplant. Many more never make the list, because they are too sick to ...