The overexpression of a gene tied to cell division and the structure and function of neurons may prevent and protect against cognitive decline in both mice and humans with Alzheimer's disease (AD), ...

A consortium of researchers has produced the largest and most advanced multidimensional maps of gene regulation networks in the brains of people with and without mental disorders. These maps detail ...

Chromosomes are thread-like structures comprising DNA that are present inside the nucleus of every cell in the body. Specific segments of DNA are called genes. Every chromosome contains many genes, ...

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...

We know the genes, but not their functions—to resolve this long-standing bottleneck in microbial research, a joint research team has proposed a cutting-edge research strategy that leverages artificial ...

A protein, the farnesoid X receptor, that is a key modulator of fat, glucose and cholesterol levels in the body usually works in tandem with another protein, but new research shows it can also work ...

Genes are specific segments of DNA that influence certain aspects of growth and health. Collectively, scientists refer to all of an organism’s genes as a genome. DNA is the genetic material or code ...

A proposed function of TADs is to contribute to gene regulation by promoting chromatin interactions within a TAD and by suppressing interactions between TADs. Here, we directly probe the ...

Scientists are uncovering how the placenta, long viewed as a temporary pregnancy organ, acts as a powerful biological predictor of lifelong health, linking prenatal environments to future risks of ...