This review highlights the critical role of ubiquitination in governing the functionality of cancer stem cells (CSCs), shedding light on potential therapeutic targets for combating tumor progression, ...

KU Leuven Center for Cancer Biology, in collaboration with the Francis Crick Institute, has discovered how cancer cells can exploit healthy lung cells to support metastatic tumor growth in the lungs.

HMGA2 is a non-histone chromatin-binding protein that has emerged as a critical regulator in both cancer progression and stem cell biology. Frequently overexpressed in various malignancies, HMGA2 ...

Scientists at University of California, San Diego (UCSD), have developed a new approach to destroying cancer stem cells (CSCs)—the hard-to-find cells that help cancers spread, come back after ...

Researchers from University of California San Diego Sanford Stem Cell Institute have discovered that spaceflight accelerates the aging of human hematopoietic stem and progenitor cells (HSPCs), which ...

Cancer scientists have been working against the clock for decades to outsmart a disease that comes back more powerfully after treatment. Traditional treatments like chemotherapy, radiation, and even ...

In a first-of-its-kind clinical trial, UCLA scientists have shown it's possible to reprogram a patient's blood-forming stem cells to generate a continuous supply of functional T cells, the immune ...

Researchers at the Icahn School of Medicine at Mount Sinai have discovered how to reverse aging in blood-forming stem cells in mice by correcting defects in the stem cell's lysosomes. The breakthrough ...

Swallowing is a fundamental human function that supports nutrition and communication. Damage to swallowing muscles can reduce ...

Researchers mapped distinct cancer cell communities within supratentorial ependymoma tumors, showing how different cell types ...