Can the weakened immune systems of older individuals be rejuvenated? Researchers from the German Cancer Research Center (DKFZ), the HI-STEM institute, and the Broad Institute have demonstrated that ...

Since addressing the COVID-19 pandemic, mRNA vaccines have risen as a promising tool for treating a broad range of diseases, such as cancer and genetic disorders. To be effective, foreign mRNA in ...

A team of researchers led by Dr. Kim V. Narry, director of the Center for RNA Research at the Institute for Basic Science (IBS), has uncovered a key cellular mechanism that affects the function of ...

Genome-wide CRISPR knockout screens to identify cellular regulators of LNP-based mRNA vaccines. mRNAs encoding Green Fluorescent Protein (GFP) were in vitro transcribed (IVT) and delivered to knockout ...

Lipid nanoparticle-delivered messenger RNA encoding anti-PD-L1 nanobodies has reduced tumour growth in sporadic and colitis-associated colorectal cancer models, with quadruple constructs that ...

With the possibility of Robert F. Kennedy, Jr. being involved in health policy in the next administration, vaccination – especially mRNA vaccines – will become a hot topic. Is there anything to fear ...

Researchers developed an mRNA delivery system designed to improve embryo implantation. This approach could enhance ART outcomes and address uterine-factor infertility, with pre-clinical studies ...