STAT

Biotech investors: Stop expecting CRISPR science to make big leaps

Banas is associate director of research at the Gene Editing Institute at ChristianaCare, where Kmiec is founder and executive director. The medical promise of CRISPR gene editing can be seen most ...
NPR

Customized CRISPR treatments could help people with rare genetic disorders

The gene-editing technique known as CRISPR is promising to revolutionize medicine. Some researchers are trying to help make it available for people with very rare genetic disorders. A gene-editing ...
Fierce Biotech

Intellia pauses phase 3 CRISPR trials after patient is hospitalized

Intellia paused both trials after receiving a report of grade 4 liver enzymes and increased total bilirubin in a patient in ...
HealthTech

Perturb-Seq in Practice: Dissecting Gene Function with CRISPR + scRNA-Seq

In modern functional genomics, understanding how specific genes control cellular behavior requires both targeted intervention and high-resolution analysis. That’s where Perturb-Seq comes in—a method ...
NPR

How CRISPR is changing the way we grow our food

How can we grow enough food without destroying our planet in the process? Physical chemist Brad Ringeisen believes CRISPR may hold the key—by helping to develop climate-resilient crops. Brad ...
Phys.org

Scientists reveal functional RNA splitting mechanism behind origin of type V CRISPR systems

CRISPR-Cas systems are adaptive immune systems found in prokaryotes that defend against invading nucleic acids through CRISPR RNA-guided cleavage. Type V CRISPR-Cas (Cas12) systems, in ...
The New England Journal of Medicine

Specificity of CRISPR-Cas9 Editing in Exagamglogene Autotemcel

We performed both homology-based and GUIDE-seq nomination of candidate off-target sites, which resulted in the testing of 5002 sites from four healthy donors (not shown). We then nominated additional ...
The Motley Fool

Where Will CRISPR Therapeutics Be in 5 Years?

CRISPR Therapeutics now has an approved product in its portfolio in Casgevy. The treatment has the potential to be a game changer for the company's business. Even with more treatments in its ...
New York Post

Could Down syndrome be eliminated? Scientists say cutting-edge gene editing tool could cut out extra chromosome

Cutting-edge gene editing technology could eradicate Down syndrome, according to Japanese scientists. Down syndrome, which causes a range of developmental differences and affects 1 in 700 newborns in ...